CY21006: Organic Chemistry Ii
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| Course name | Organic Chemistry Ii | ||||||||||||||||||||
| Offered by | Chemistry | ||||||||||||||||||||
| Credits | 3 | ||||||||||||||||||||
| L-T-P | 2-1-0 | ||||||||||||||||||||
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| Semester | Spring | ||||||||||||||||||||
Syllabus
Syllabus mentioned in ERP
Prerequisite: CY20103 Nucleophilic addition to C=X (X = O, NR): Simple addition reactions: Structure and reactivity, addition of alcohols, thiols, hydrogen cyanide, bisulphite and other anions, hydride ions, complex metal hydride ions; Meerwein-Ponndorf âVerley reduction, Cannizzaro reaction, Clemmensen reduction, Beckmann rearrangement. Carbon nucleophile addition: Grignard reagents, acetylide anions, other carbanions, stereoselectivity (Cramâs Rule); aldol reactions and its stereoselectivity (syn- & anti-aldol), Enamine Chemistry, Mannich reaction, Henry reaction, Perkin reaction, Knoevenagel and Stobbe reactions, Claisen ester condensation, Benzoin condensation, Benzilic acid rearrangement, Darzens glycidic ester condensation, Reformatsky reaction, Baeyer-Villiger oxidation, Favorski rearrangement, McMurry coupling, Michael reaction (1,4-conjugate addition) to C=C-C=O systems, Robinson annulation, Baylis-Hilmann reaction. Active methylene compounds: alkylation, conjugate addition, synthesis of different structural unit using active methylene compounds. Books: A Guide book to Mechanism in Organic Chemistry by Peter Sykes Organic Chemistry by Clayden, Greeves, Warren and Wothers