CY41014: Principles Of Organometallics And Bioinorgnic Chemistry
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| Course name | Principles Of Organometallics And Bioinorgnic Chemistry | ||||||||||||||||||||||||||||
| Offered by | Chemistry | ||||||||||||||||||||||||||||
| Credits | 4 | ||||||||||||||||||||||||||||
| L-T-P | 4-0-0 | ||||||||||||||||||||||||||||
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| Semester | Spring | ||||||||||||||||||||||||||||
Syllabus
Syllabus mentioned in ERP
CY40110 Principles of Organometallic and Bioinorganic Chemistry (4-0-0 : 4 credits) Prerequisite : CY40101 Organometallic chemistry: Bonding models in sigma and pi-complexes. 18-electron formalism and isolobal principle. Basic concepts guiding the synthesis and stability of Li, Mg, B, Si organometallic compounds. Wades/Mingos/Jemmis rule. Basic concepts guiding the synthesis and stability of transition metal alkyls, carbonyls, alkenes, alkynes, arenes, allyls, carbenes, and metallocenes. Basic organometallic reactions: oxidative-addition, reductive elimination, transmetallation, insertion, nucleophilic attach on coordinated ligand. Typical examples of fluxional organometallics. Bioinorganic Chemistry: The biochemistry of iron and copper: Dioxygen binding, transport and utilization in hemoglobin, hemocyanin and hemerythrin. Biological and synthetic dioxygen carriers. Metal-sulfide proteins: Ferredoxin and nitrogenases. Metalloporphyrins and Respiration: Cytochromes. Electron transfer reactions. Metalloenzymes: Carbonic anhydrase, carboxypeptidase and vitamin B12. Books: Inorganic Chemistry by J.E. Huheey The Organometallic Chemistry of The Transition Metals, by R.H. Crabtree Principles & Applications of Organo-transition Metal Chemistry, by J.P. Collman, L.S. Hegedus, J.R. Norton, R.G. Finke Bioinorganic Chemistry by Lippard, and Bartini